Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders

This is a long-term registry and biobank study collecting blood, tissue, and health data from people with congenital heart disease and related conditions. The goal is to better understand these diseases over time and improve how they are diagnosed and treated. **You may be eligible if...** - You are 16 years or older - You have been diagnosed with or suspected of having congenital heart disease, another heart or blood vessel condition, pulmonary hypertension, a connective tissue disorder, or a genetic syndrome - You are a healthy volunteer (family member or friend accompanying a patient), without a history of diabetes, heart attack, stroke, heart failure, or chronic kidney disease - You are a person with heart failure or pulmonary hypertension but without congenital heart disease (comparison group) **You may NOT be eligible if...** - You cannot give informed consent yourself or through a legal guardian - A doctor or study team member determines it is not safe to collect a blood or tissue sample from you - You were hospitalized overnight (for a non-pregnancy reason) within the past 30 days Talk to your doctor to see if this trial is right for you.