Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia

This study evaluates a new ultraviolet (UV) light system called PXL-Platinum 330 for corneal cross-linking — a procedure that strengthens the cornea to slow or stop the progression of keratoconus or other corneal thinning conditions. You may be eligible if: - You are 10 years old or older - You have keratoconus, post-surgical ectasia, or pellucid marginal degeneration confirmed by eye examination and imaging - Your cornea's thinnest point is at least 300 microns You may NOT be eligible if: - Your cornea is classified as normal on testing - Your cornea is thinner than 300 microns at the thinnest point - You have active corneal disease (e.g., herpes simplex, recurrent corneal erosion) - You are pregnant, planning pregnancy, or breastfeeding - You have a known allergy to study eye drops - You have a condition that prevents you from holding a steady gaze Talk to your doctor to see if this trial is right for you.