RecruitingNCT04130971

Predicting Colorectal Cancer - Tissue Samples to Evaluate Tumour Characteristics and Treatment Response

Predict - a Translational Study to Predict Tumour Response to Neoadjuvant Treatment


Sponsor

Sahlgrenska University Hospital

Enrollment

800 participants

Start Date

Feb 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

All adult patients with colorectal cancer presenting within the Sahlgrenska University Hospital or treated at any time at Sahlgrenska University Hospital are eligible and will be asked to participate. We already have biopsies taken at surgery in patients that receive surgery, but this study will include all patients and the biopsies will be taken during endoscopy for diagnosis of the primary tumour. Biopsies will then be taken during follow-up exams prior surgery but after neoadjuvant treatment. Biopsies will also be taken during surgery and in cases where surgery is not necessary biopsies will be taken regularly during follow-up exams. Blood samples and in relevant cases urinary samples and mouth swabs will be taken at all timepoints when biopsies are taken. If it is not possible to take biopsies prior treatment blood samples will still be drawn.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Colorectal cancer

Exclusion Criteria1

  • Not colorectal cancer

Interventions

OTHERNo intervention, just observation

No intervention, just observation of the differences between groups and within patients.


Locations(1)

Dept. of Surgery, Sahlgrenska University Hospital/Ostra

Gothenburg, Sweden

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NCT04130971


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