Imaging Biomarkers in Preclinical and Symptomatic AD

This study is using brain imaging (including PET and MRI scans) to look for early biological markers of Alzheimer's disease before symptoms appear, in people who are part of an established Alzheimer's disease research center at Washington University. **You may be eligible if...** - You are 18 or older, any race or gender - You are currently enrolled in the Knight Alzheimer's Disease Research Center at Washington University **You may NOT be eligible if...** - You have a sensitivity or allergy to the imaging agent used (PIB) - You have a pacemaker, metal implants, severe claustrophobia, or another reason you cannot safely have MRI or PET scans - You are pregnant or breastfeeding - You have participated in radioactive research studies recently enough that additional radiation would exceed safe limits - You are currently in another clinical trial involving an active study drug Talk to your doctor to see if this trial is right for you.