Radical Local vs. Palliative Therapy for Breast Cancer Patientts With Ipsilateral Humerus or Sternum Oligometastasis

This study is comparing two treatment approaches for women with breast cancer that has spread (metastasized) only to the bone in the shoulder (humerus) or breastbone (sternum) — a situation called oligometastasis (very limited spread). One approach is radical local treatment (aggressive targeted therapy to the metastatic site) versus standard palliative therapy. The goal is to see if aggressively treating the single metastatic site improves survival. **You may be eligible if...** - You are a woman between 18 and 75 years old - You have histologically confirmed breast cancer and have had a mastectomy - Your cancer has spread only to the ipsilateral (same-side) humerus or sternum, with no other metastases visible on imaging - Your blood counts and organ function meet acceptable thresholds - You do not have HIV **You may NOT be eligible if...** - There is evidence of cancer spread to any other location - You have not recovered from side effects of previous treatments Talk to your doctor to see if this trial is right for you.