RecruitingPhase 3NCT04161053

Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy

Clinical Study Evaluating the Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy


Sponsor

Tanta University

Enrollment

60 participants

Start Date

Nov 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

Efficacy and Safety of Nitazoxanide in preventing recurrence of Hepatic Encephalopathy.


Eligibility

Min Age: 20 YearsMax Age: 65 Years

Inclusion Criteria2

  • Cirrhotic patient with at least one previous episode of hepatic encephalopathy.
  • Adult Patients aging from 20 to 65 years old

Exclusion Criteria3

  • Active GIT bleeding.
  • Major psychiatric illness (psychosis \& epilepsy).
  • Renal insufficiency (S.Cr 2mg/dl).

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Interventions

DRUGRifaximin

Rifaximin 550 mg twice daily for 6 months

DRUGNitazoxanide

Nitazoxanide 500 mg twice daily for 6 months


Locations(1)

Sherief Abd-Elsalam

Tanta, Egypt

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NCT04161053


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