Hepatic Encephalopathy Clinical Trials

16 recruiting

Hepatic Encephalopathy Trials at a Glance

20 actively recruiting trials for hepatic encephalopathy are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in New York, Cleveland, and Atlanta. Lead sponsors running hepatic encephalopathy studies include Asian Institute Of Medical Sciences, Asian Institute of Gastroenterology, India, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse hepatic encephalopathy trials by phase

Treatments under study

About Hepatic Encephalopathy Clinical Trials

Looking for clinical trials for Hepatic Encephalopathy? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hepatic Encephalopathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hepatic Encephalopathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 4

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

CirrhosisAscitesPortal Vein Thrombosis+3 more
Asian Institute Of Medical Sciences220 enrolled1 locationNCT07521332
Recruiting
Phase 2

Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement

CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06052176
Recruiting
Phase 2

TReatment for ImmUne Mediated PathopHysiology

Hepatic EncephalopathyAcute Liver FailureFulminant Hepatic Failure
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)163 enrolled24 locationsNCT04862221
Recruiting

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

Cognitive DysfunctionLiver CirrhosisNeurocognitive Disorders+1 more
University of Malaya230 enrolled1 locationNCT07418008
Recruiting
Not Applicable

Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy

CirrhosisHepatic Encephalopathy
Mayo Clinic11 enrolled2 locationsNCT06425380
Recruiting
Not Applicable

Underdilated-stent Technique Improves Post-TIPS Encephalopathy

Liver CirrhosisAscites HepaticVariceal Bleeding, Cirrhosis+1 more
The Second Affiliated Hospital of Chongqing Medical University72 enrolled2 locationsNCT07349654
Recruiting
Not Applicable

Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Hepatic Encephalopathy
The Cleveland Clinic40 enrolled1 locationNCT04096014
Recruiting

VICIS - Vienna Cirrhosis Study

AscitesLiver CirrhosisPortal Hypertension+2 more
Medical University of Vienna10,000 enrolled1 locationNCT03267615
Recruiting
Not Applicable

Affect of Melatonin on Sleep and Cognition in Cirrhosis

CirrhosisHepatic EncephalopathyCovert Hepatic Encephalopathy+1 more
Weill Medical College of Cornell University18 enrolled1 locationNCT07046429
Recruiting
Not Applicable

Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)

Overt Hepatic Encephalopathy
General Hospital of Shenyang Military Region174 enrolled1 locationNCT06483737
Recruiting
Phase 4

BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HE

Hepatic EncephalopathyDecompensated Cirrhosis
Post Graduate Institute of Medical Education and Research, Chandigarh336 enrolled1 locationNCT06538077
Recruiting

Correlation Between Serum Albumin Level and Severity of Hepatic Encephalopathy in Patients With Chronic Liver Disease in Sohag University Hospital

Hepatic Encephalopathy
Sohag University100 enrolled1 locationNCT06953921
Recruiting
Phase 4

A Study to Evaluate Role of Inhaled Amikacin to Prevent Ventilator Associated Pneumonia in Patients With Cirrhosis

CirrhosisHepatic Encephalopathy
Asian Institute of Gastroenterology, India162 enrolled2 locationsNCT06808074
Recruiting
Phase 4

Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose

Liver DiseasesCirrhosis, LiverPortal Hypertension+2 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)238 enrolled6 locationsNCT04073290
Recruiting
Not Applicable

Safety and Efficacy of Fecal Microbiota Transplantation

AlopeciaDiabetes MellitusObesity+18 more
Chinese University of Hong Kong450 enrolled1 locationNCT04014413
Recruiting
Not Applicable

Hepatic Encephalopathy Prevention With Polydextrose After TIPS: Pilot Study (POEME)

Hepatic Encephalopathy
University Hospital, Toulouse30 enrolled1 locationNCT05206487
Recruiting

Prospective Cohort Study of Complications and Outcomes in Cirrhosis

Decompensated CirrhosisCMV ReactivationOvert Hepatic Encephalopathy
Nanfang Hospital, Southern Medical University660 enrolled1 locationNCT06374511
Recruiting
Phase 1

Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy Treatment

DysbiosisHepatic Encephalopathy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS60 enrolled1 locationNCT06368895
Recruiting
Phase 3

Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy

Hepatic Encephalopathy
Tanta University60 enrolled1 locationNCT04161053
Recruiting

Sevoflurane aggravate minimal hepatic encephalopath in cirrhosis patients

minimal hepatic encephalopathy
National Natural Science Foundation of China60 enrolled1 locationACTRN12612000910808