Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

This study is looking at whether treating sleep apnea with CPAP (a machine that keeps your airway open during sleep) improves health outcomes in older veterans who also have COPD (a chronic lung disease). **You may be eligible if...** - You are 60 years or older - You have moderate-to-severe sleep apnea (confirmed by a sleep study) AND moderate-to-severe COPD (confirmed by lung function tests) - You have a significant history of smoking (more than 10 pack-years) - You have not previously used CPAP or a dental device for sleep apnea **You may NOT be eligible if...** - You already use CPAP or a mouth appliance - You have central sleep apnea (a different type from obstructive sleep apnea) - You are currently on a ventilator - You have severe oxygen-dependent lung disease or end-stage heart failure Talk to your doctor to see if this trial is right for you.