RecruitingNot ApplicableNCT04190953

Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

Skeletal, Dental and Upper Airway Changes in Skeletal Class II Division 1 Patients With the Constricted Maxilla (8-14 Years Old) Treated With Twin Block and Hyrax, Evaluated Through Pressure Drop Experimental Analysis.


Sponsor

University of Alberta

Enrollment

90 participants

Start Date

Feb 18, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least. But what if orthodontic treatment could help those patients to breathe better, with less effort? This research proposal aims to find out if the increase in the upper airway volume seen in some research results can be related to a decrease in respiratory effort and an improvement in the breathing capacity of those patients. In other words, if a tube shape is changed or if a tube is enlarged, would the airflow passing inside the tube change in velocity? Or would there be more air? Therefore, investigating the pressure/airflow, volume/lumen relation and its possible changes after mandibular repositioning and maxillary expansion in children will lead to a better understanding of how orthodontics could potentially affect the upper airway. Previous studies have reported a link between mandibular advancement appliances and maxillary appliances to an increase in the upper airway volume. However, more studies are needed to evaluate the relationship between the changes in the upper airway volume and actual airflow and respiratory capability. The airway volume measurement is important to, preliminary, state if there is an increase in the upper airway after orthodontic treatment. However a change in shape, even with the same volume, can affect the pressure and airflow. In this sense, the pressure drop analysis will allow an answer to those questions


Eligibility

Min Age: 8 YearsMax Age: 14 Years

Plain Language Summary

Simplified for easier understanding

This study measures changes in upper airway air pressure in children undergoing orthodontic treatment for a specific type of jaw misalignment — Class II division 1 malocclusion with a narrow upper jaw (maxillary constriction). Treatments include a mandibular advancement device (to move the lower jaw forward) and a palatal expander (to widen the upper jaw). Narrow upper jaws and overbites can contribute to breathing difficulties, and this study uses airflow measurements to understand how these orthodontic treatments affect breathing. Children aged 8 to 14 with this specific dental and jaw structure are enrolled before starting orthodontic treatment, with airway measurements taken before and after the interventions. You may be eligible if... - Your child is between 8 and 14 years old (girls 8–12, boys 9–14) - Your child has a Class II division 1 malocclusion (overjet/overbite) with a narrow upper jaw You may NOT be eligible if... - Your child has a syndrome or genetic condition affecting jaw or face development - Your child has had prior orthodontic treatment - Your child has severe dental health issues such as cavities or very poor oral hygiene - Your child is unlikely to comply with orthodontic treatment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTwin block then Hyrax

Patients will undergo mandibular advancement prior to maxillary expansion

OTHERHyrax then Twin block

Patients will undergo maxillary expansion prior to mandibular advancement


Locations(1)

University of Alberta

Edmonton, Alberta, Canada

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NCT04190953


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