RecruitingNot ApplicableNCT06659887

Different Low Flow Rates on Gas Exchange in Children During Apnea

Effect of Different Low Flow Rates on Gas Exchange in Anesthetized Children During Apnea A Single Blinded Randomized Study

Sponsor

Yasser S Mostafa, MD

Enrollment

60 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Apnea

Summary

Effect of Low flow apneic oxygenation in pediatrics on rate of accumulation of transcutaneous carbon dioxide also, had been studied, compared to high flow rates. Furthermore, a recent study in apneic anesthetized adult discussed the rate of accumulation of carbon dioxide in arterial blood during 4 min of apnea but, no study in pediatrics discussed the effect of different low flow rates on rate of carbon dioxide accumulation during a period of apnea. Aim of the study: the authors aim to study the effect of different flow rates of low flow oxygenation during 3 min of apnea in anesthetized children on the rate of accumulation of carbon dioxide

Eligibility

Min Age: 1 YearMax Age: 6 Years

Inclusion Criteria3

Children aged 1 to 6 years old weighting 10-20 kg.
American Society of Anesthesiologists (ASA) physical status I or II.
Children will be scheduled for elective surgery under general anesthesia.

Exclusion Criteria7

Parent refusal
Patient required nasal intubation
Children with a cardio-respiratory disease like asthma or recent upper respiratory infection.
Anemia.
Obstructive sleep apnea, sepsis.
Children prone to hypoxia or hypercarbia, and upper airway obstruction.
Children reported to have nasal obstruction .

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Interventions

DEVICEnasal cannula

After induction, bag-mask ventilation with 100% oxygen and flow rates of 6 L/ min will be carried out until the expired oxygen concentration will be \>90%, saturation of oxygen was 100%, and end tidal carbon dioxide was 30-40 mmHg. Once this will be reached, bag-mask ventilation will be stopped and apneic oxygenation will be initiated for 3 minutes