RecruitingNCT04198740

Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Enrollment

300 participants

Start Date

Feb 1, 2020

Study Type

OBSERVATIONAL

Conditions

allergic conjunctivitis dry eye syndrome Mucous Membrane Pemphigoid Infectious Keratoconjunctivitis

Summary

This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.

Eligibility

Min Age: 18 Years

Inclusion Criteria2

Patients with healthy corneas or suffering from one of these pathologies:
Dry eye syndrome; Infectious keratitis and/or conjunctivitis; Mucous membrane pemphigoid; Allergic conjunctivitis.

Exclusion Criteria2

Patients younger than 18 years old;
Patients incapable of giving informed consent.

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Interventions

DIAGNOSTIC_TESTTear sample collection via Schirmer strip and subsequent analysis by mass spectrometry

During regular consultations at the ophthalmology department of the CHUM, eligible patients will undergo a standard 5 minute Schirmer tear test. The Schirmer strips will serve as tear samples and will be sent to UQAM's Department of chemistry for mass spectrometry analysis.