RecruitingNCT04258787
OCT in Fuchs' Dystrophy
Evaluating Corneal Edema in Fuchs' Endothelial Dystrophy Using Optical Coherence Tomography
Sponsor
Oregon Health and Science University
Enrollment
60 participants
Start Date
Jun 26, 2020
Study Type
OBSERVATIONAL
Conditions
Summary
This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.
Eligibility
Min Age: 18 Years
Inclusion Criteria2
- Damaged or diseased corneal endothelium from Fuchs' or PBK
- Willingness to commit to required study visits
Exclusion Criteria8
- Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery
- Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis)
- Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome)
- Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment
- Peripheral anterior synechiae in the angle greater than 3 clock hours
- Hypotony
- Uncontrolled glaucoma
- Visually significant optic nerve or macular pathology
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04258787
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