Descemet Endothelial Thickness Comparison Trial II

This study compares two surgical techniques for corneal transplantation in patients with Fuchs' Endothelial Corneal Dystrophy (FECD), a disease where the inner layer of the cornea degrades over time, causing blurred vision. Researchers want to find out which type of transplant leads to better vision and faster recovery. You may be eligible if: - You are 18 years or older - You have FECD with guttata (bumps on the cornea) extending beyond 4.5 mm - Your peripheral endothelial cell count is over 1000 cells/mm² in at least one quadrant - You are considered a good surgical candidate by the surgeon You may NOT be eligible if: - You have significant scarring in the central cornea affecting vision - You have another primary corneal endothelial condition (e.g., PPMD) - You have significant optic nerve or macular disease - You have low eye pressure (below 10 mmHg) - You have had any prior eye surgery other than cataract surgery - You have extensive synechiae (adhesions inside the eye) - You are pregnant Talk to your doctor to see if this trial is right for you.