Forced Oscillometry in Infants With Bronchopulmonary Dysplasia
Winston Manimtim
80 participants
Feb 6, 2020
OBSERVATIONAL
Conditions
Summary
The purpose of this study is to use forced oscillometry technique (FOT) to measure pulmonary mechanics and function in in term infants and premature infants with bronchopulmonary dysplasia (BPD)
Eligibility
Inclusion Criteria9
- Preterm Cohort:
- Premature infants with BPD who are in room air based on the (per NICHD definition)
- Premature infants with BPD who are receiving low flow O2 support and able to maintain normal spO2 in Room air for brief period ( up to 3 minutes) Term Cohort without pulmonary disease
- Infants \>36 weeks gestational age without pulmonary disease
- Infants \< 4 weeks of age
- Outpatient Cohort:
- Former preterm infants \< 32 weeks at birth
- Those with BPD based on NIH 2001 definition
- Seen prior to 2 years of age
Exclusion Criteria2
- Infants with BPD requiring invasive or non-invasive positive pressure ventilation
- Infants with BPD who have associated genetic diagnosis or major congenital anomalies.
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Interventions
This non-invasive device will measure pulmonary mechanics in spontaneously breathing premature infants and term infants without pulmonary disease. Infant will be in supine position and breathing regularly. A cushioned mask will be placed on the infant's face, covering the nose and mouth. Measurements typically take less than 20 seconds and no more than 3 repetitions will be done at each time point.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04270045