RecruitingNCT04275557

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas and Uncover Hidden Biology


Sponsor

H. Lee Moffitt Cancer Center and Research Institute

Enrollment

1,174 participants

Start Date

Feb 18, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is researching pancreatic cysts — fluid-filled sacs in the pancreas — to learn which ones are likely to become cancerous. By combining imaging with genetic information, researchers hope to develop better tools to predict which cysts need treatment and which can simply be monitored. **You may be eligible if...** - You have a known or suspected pancreatic cyst, mass, or cancer detected on imaging or during a clinical visit - You are being seen at Moffitt Cancer Center or affiliated clinics - You have not yet received any treatment for a pancreatic condition - You are willing to share medical images and biological samples **You may NOT be eligible if...** - You have already had treatment involving your pancreas - You are unwilling to sign the consent form or complete questionnaires Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBlood Sample collection

Participants will be asked to donate blood at baseline (+/- 30 days of diagnosis date), 4-6 weeks post-surgery, if applicable, and at the time of follow-up (approximately 1 year and approximately 2 years after baseline).

OTHERTissue sample collection

At the time of tissue biopsy and surgical resection (if applicable), pancreatic tumor tissue, muscle, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.

OTHERData collection

Participants will be asked to complete questionnaires at baseline and at 1 year and 2 year follow-ups.


Locations(3)

Florida Research Institute (FRI)

Lakewood Rch, Florida, United States

Sylvester Comprehensive Cancer Center & Jackson Memorial Hospital

Miami, Florida, United States

Moffitt Cancer Center

Tampa, Florida, United States

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NCT04275557


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