Identification of Critical Thermal Environments for Aged Adults
Penn State University
190 participants
Dec 30, 2020
INTERVENTIONAL
Conditions
Summary
This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate. Participants will exercise in a series of different environmental conditions to identify combinations of temperature and humidity above which age-related physiological changes cause uncompensable heat stress, resulting in increased risk of heat illness.
Eligibility
Inclusion Criteria3
- Adults aged 18 and older (those 40+ years of age must be cleared by collaborating physician)
- All premenopausal women will be eumenorrheic (by survey)
- Asymptomatic and no signs/symptoms of disease according to the American College of Sports Medicine 10th edition Guidelines for Exercise Testing and Prescription
Exclusion Criteria8
- Medications that affect thermoregulatory or cardiovascular responses to exercise
- Any contraindications to low intensity physical activity on the Physical Activity Readiness Questionnaire
- Any mobility restrictions that interfere with low intensity physical activity
- Pregnant or planning to become pregnant in the next 12 months
- Prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
- Illegal/recreational drug use
- History of Chron's disease, diverticulitis, or similar gastrointestinal disease
- Abnormal resting or exercise electrocardiogram (ECG)
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Interventions
A sub-group of older adults will be re-tested after 7 days of treatment with low-dose aspirin.
All participants will be tested with no treatment.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04284397