RecruitingNot ApplicableNCT04307615

O2 Versus CPAP Treatment of Patients Undergoing SIPE Therapy (OCTOPUS)

Evaluation of Continous Positive Airway Pressure (CPAP) in Swimming Induced Pulmonary Edema (SIPE) -a Randomized Single-blinded Controlled Study


Sponsor

Dalarna County Council, Sweden

Enrollment

90 participants

Start Date

Jul 2, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

In swimming induced pulmonary edema (SIPE), there is a lack of knowledge regarding optimal treatment. The present study was designed to assess the benefit of continuous positive airway pressure (CPAP) compared to oxygen as a first line treatment of SIPE in the out-of-hospital environment.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment (oxygen saturation ≤91%)
  • years and older
  • informed consent

Exclusion Criteria4

  • declined consent
  • suspected acute coronary syndrome
  • severe asthma diagnosed together with pulmonary edema where beta-agonist-inhalation is needed prior to treatment of pulmonary edema
  • hemodynamic instability or decreased consciousness

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Interventions

COMBINATION_PRODUCTOxygen + continuous positive airway pressure (CPAP)

Oxygen-driven CPAP (7,5 cmH2O): 20 min treatment followed by 10 min rest and assessment

DRUGOxygen

Oxygen: 20 min treatment followed by 10 min rest and assessment


Locations(1)

Center of Clinical Research Dalarna

Falun, Sweden

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NCT04307615


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