Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

This study examines a type of immune cell called monocytes in people who have experienced different types of ischemic (blood flow–blocking) vascular disease — including heart attacks, unstable angina, and strokes. Researchers believe these cells play an important role in how the blood vessel damage and inflammation unfolds after a cardiovascular event. Blood samples are collected from participants and analysed to understand how monocytes differ between people with different types of vascular disease and compared to healthy volunteers without any heart or vascular conditions. You may be eligible if: - You are 18 years of age or older - You have had a recent heart attack (STEMI or NSTEMI), have stable coronary artery disease, or have experienced an ischemic stroke - OR you are a healthy adult with no history of heart or vascular disease (as a comparison volunteer) You may NOT be eligible if: - You are unable to give informed consent - You have had a stroke or other embolic event within the last 12 months (for non-stroke groups) - You are pregnant Talk to your doctor to see if this trial is right for you.