Ischemia Clinical Trials

184 recruitingLast updated: June 18, 2026

There are 184 actively recruiting ischemia clinical trials across 40 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include New York, New York, United States, San Francisco, California, United States, Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Ischemia Trials at a Glance

184 actively recruiting trials for ischemia are listed on ClinicalTrialsFinder across 6 cities in 40 countries. The largest study group is Not Applicable with 72 trials, with the heaviest enrollment activity in New York, San Francisco, and Cleveland. Lead sponsors running ischemia studies include Oslo University Hospital, Assistance Publique - Hôpitaux de Paris, and Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

Treatments under study

About Ischemia Clinical Trials

Looking for clinical trials for Ischemia? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Ischemia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Ischemia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 184 trials

Recruiting
Not Applicable

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

Arterial Occlusive DiseasesPainCardiovascular Diseases+12 more
Teleflex1,859 enrolled1 locationNCT07258290
Recruiting

NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemia

Critical Ischemia Limb
University Hospital, Angers200 enrolled3 locationsNCT06238050
Recruiting
Not Applicable

Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia Stage

Peripheral Artery DiseaseMajor Adverse Cardiovascular EventsMajor Adverse Limb Events+2 more
Centre Hospitalier Universitaire, Amiens134 enrolled1 locationNCT06318767
Recruiting
Not Applicable

FAZA PET/MRI in CLI Patients Pre and Post Revascularization

Critical Limb Ischemia
University Health Network, Toronto40 enrolled1 locationNCT04054609
Recruiting

Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

Peripheral Arterial DiseaseDVTAcute Limb Ischemia+8 more
Medtronic Endovascular50 enrolled2 locationsNCT07335341
Recruiting
Not Applicable

Intravascular Ultrasound for Peripheral Artery Disease Revascularization

Chronic Limb Threatening IschemiaPeripheral Arterial Disease(PAD)Restenosis+2 more
Hamilton Health Sciences Corporation772 enrolled2 locationsNCT06979284
Recruiting

Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography

Chronic Coronary SyndromeAngina, StablePercutaneous Coronary Intervention (PCI)+1 more
Fundacion Investigacion Interhospitalaria Cardiovascular246 enrolled5 locationsNCT07638137
Recruiting
Not Applicable

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

Cardiac Arrest, Out-Of-HospitalHypoxia-Ischemia, BrainHypothermia, Induced
University of Michigan900 enrolled61 locationsNCT05376267
Recruiting

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Lower Extremity Acute Limb IschemiaLE ALI
Penumbra Inc.300 enrolled37 locationsNCT06747117
Recruiting

Predictors of Transmural Non-Occlusive Mesenteric Ischemia in ICU Patients With Suspected Acute Mesenteric Ischemia

Acute Mesenteric IschemiaNon-Occlusive Mesenteric Ischaemia (NOMI)
University of Tartu150 enrolled2 locationsNCT07610356
Recruiting
Not Applicable

Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)

Cardiovascular DiseasesMyocardial IschemiaHeart Diseases+3 more
VahatiCor, Inc.30 enrolled2 locationsNCT07449325
Recruiting
Not Applicable

Neonate Cerebral Activity in Immediate Post Partum

Neonatal EncephalopathyAnoxia-Ischemia, Brain
Centre Hospitalier Universitaire, Amiens60 enrolled1 locationNCT04225975
Recruiting

Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries

Neuropathy;PeripheralLimb Ischemia
The University of Texas Health Science Center, Houston30 enrolled2 locationsNCT07387653
Recruiting
Not Applicable

Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease

intermittent claudicationstable coronary artery diseaseAcute Coronary Syndromes+1 more
Maria Cecilia Hospital60 enrolled1 locationNCT07588295
Recruiting

Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study

Chronic Limb Threatening Ischemia
Cardiovascular and Interventional Radiological Society of Europe400 enrolled39 locationsNCT06149650
Recruiting
Phase 2

Efficacy of Daily IV Administration of Dornase Alfa up to 14 Days Post Subarachnoid Hemorrhage on Functional Independence at 6 Months

SAH (Subarachnoid Hemorrhage)Delayed Cerebral IschemiaRuptured Aneurysm of Intracranial Artery
Fondation Ophtalmologique Adolphe de Rothschild304 enrolled6 locationsNCT06723717
Recruiting

AI-assisted CT for Risk Stratification in Coronary Artery Disease (ACTION)

AI (Artificial Intelligence)BiomarkersMyocardial Ischemia+4 more
University of Galway10,000 enrolled1 locationNCT07577609
Recruiting
Not Applicable

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

ANOCA - Angina With Non-obstructive Coronary ArteriesINOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Baylor Research Institute50 enrolled1 locationNCT06896903
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and Pharmacokinetics of Regadenoson in Pediatric Patients

Myocardial IschemiaCoronary Artery Disease
GE Healthcare54 enrolled5 locationsNCT04604782
Recruiting
Not Applicable

SELUTION4BTK Trial

Peripheral Arterial DiseaseChronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
M.A. Med Alliance S.A.376 enrolled48 locationsNCT05055297