Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer
NRG Oncology
686 participants
Sep 23, 2020
INTERVENTIONAL
Conditions
Summary
This phase II/III trial studies how well sentinel lymph node biopsy works and compares sentinel lymph node biopsy surgery to standard neck dissection as part of the treatment for early-stage oral cavity cancer. Sentinel lymph node biopsy surgery is a procedure that removes a smaller number of lymph nodes from your neck because it uses an imaging agent to see which lymph nodes are most likely to have cancer. Standard neck dissection, such as elective neck dissection, removes many of the lymph nodes in your neck. Using sentinel lymph node biopsy surgery may work better in treating patients with early-stage oral cavity cancer compared to standard elective neck dissection.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Undergo chest x-ray
Undergo SPECT/CT scan and FDG PET/CT or CT
Undergo FDG PET/CT
Receive imaging agent via injection
Undergo standard elective neck dissection
Undergo planar imaging
Undergo FDG PET/CT
Ancillary studies
Undergo SLN biopsy
Undergo SPECT/CT scan
Locations(106)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04333537