The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function
Auburn University
60 participants
Oct 2, 2020
INTERVENTIONAL
Conditions
Summary
Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influence blood vessel function and nervous system regulation of blood pressure differentially in black, compared to white individuals. These findings may help to explain a potential mechanism that contributes to racial disparities in blood pressure and cardiovascular disease risk. A secondary goal is to determine if mitochondrial reactive oxygen species improves blood pressure and vascular function in individuals with elevated blood pressure and stage 1 hypertension.
Eligibility
Plain Language Summary
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Interventions
Four to eight 20mg capsules (depending on body mass)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04334135