RecruitingNot ApplicableNCT04353804

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III Pilot Randomized Clinical Trial (RETURN-III Pilot RCT)


Sponsor

VA Office of Research and Development

Enrollment

160 participants

Start Date

Oct 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Millions of patients survive care in medical and surgical Intensive Care Units (ICUs) every year, only to suffer from a new or accelerated dementia-like process, called post-ICU long-term cognitive impairment (ICU-LTCI). ICU-LTCI causes considerable problems with personal relationships, return to work, and everyday tasks, such as managing medicines and money. No treatment for these patients is currently available. Technology using computerized cognitive rehabilitation could improve ICU-LTCI by harnessing the healing potential of the brain (i.e., neuroplasticity). This intervention is scalable, portable, and economical. The investigators will evaluate the effectiveness of computerized cognitive rehabilitation in a randomized controlled trial of 160 ICU survivors. The investigators hypothesize that this intervention could improve cognition. This research has high potential to influence rehabilitation strategies for Veteran and civilian ICU survivors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Active Control computer games and Treatment Arm: Computerized Cognitive Rehabilitation for people with cognitive rehabilitation, icu, and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTreatment Arm: Computerized Cognitive Rehabilitation

Treatment Arm: Computerized Cognitive Rehabilitation

OTHERActive Control computer games

Active Control computer games


Locations(2)

Tennessee Valley Healthcare System Nashville Campus, Nashville, TN

Nashville, Tennessee, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

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NCT04353804


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