Intensive Care Unit Clinical Trials

122 recruitingLast updated: June 18, 2026

There are 122 actively recruiting intensive care unit clinical trials across 39 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2. Top locations include London, United Kingdom, Toronto, Ontario, Canada, Nantes, France. Updated daily from ClinicalTrials.gov.


Intensive Care Unit Trials at a Glance

122 actively recruiting trials for intensive care unit are listed on ClinicalTrialsFinder across 6 cities in 39 countries. The largest study group is Not Applicable with 49 trials, with the heaviest enrollment activity in London, Toronto, and Nantes. Lead sponsors running intensive care unit studies include Nantes University Hospital, Centre Hospitalier de Saint-Denis, and Assistance Publique - Hôpitaux de Paris.

Browse intensive care unit trials by phase

Treatments under study

About Intensive Care Unit Clinical Trials

Looking for clinical trials for Intensive Care Unit? There are currently 23 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Intensive Care Unit trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Intensive Care Unit clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 122 trials

Recruiting
Not Applicable

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Septic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
University Hospital, Clermont-Ferrand750 enrolled28 locationsNCT07179276
Recruiting
Not Applicable

Preventive Narrative Exposure Intervention for PTSD in ICU Patients After Cardiopulmonary Bypass Cardiac Surgery

Stress Disorders, Post-TraumaticCardiopulmonary BypassIntensive Care Units
First Affiliated Hospital of Fujian Medical University100 enrolled1 locationNCT07632131
Recruiting

Muscle Recovery After Critical Illness

ICU acquired weaknessMuscle WeaknessCritical Illness+1 more
Kirby Mayer209 enrolled3 locationsNCT05537298
Recruiting
Phase 2

Adjunctive Fludrocortisone in Septic Shock

SepsisSeptic ShockSepsis and septic shock+2 more
Chinese University of Hong Kong32 enrolled5 locationsNCT07451886
Recruiting

Effect of Protein Dosage on Persistent Acute Renal Failure in Critically Ill Patients.

Critical IllnessAcute Kidney FailureNutritional Support+2 more
Hospital Italiano de Buenos Aires344 enrolled6 locationsNCT07631221
Recruiting
Not Applicable

Prevention of Delirium in ICU Using Multimodal Interventions

Intensive Care Unit Delirium
Seoul National University Hospital196 enrolled1 locationNCT05950958
Recruiting

Factor Associated With Mortality in the ICU

Intensive Care MedicineMortalityCritically Ill+3 more
Hospital Departamental de Villavicencio1,000 enrolled1 locationNCT07249749
Recruiting
Not Applicable

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

Weaning Invasive Mechanical VentilationWeaning-induced Pulmonary EdemaWeaning Failure of Mechanical Ventilation+2 more
Centre Hospitalier Régional d'Orléans24 enrolled1 locationNCT06923267
Recruiting
Not Applicable

Hemodynamic Impact of the Administration of PAracetamol in Patients Hospitalized in the Intensive Resuscitation Medicine Department [PAREA]

Intensive Care Unit Syndrome
Centre Hospitalier Universitaire de Nice200 enrolled1 locationNCT06430697
Recruiting

Pulmonary Microbiota Changes and Clinical Outcomes in Neurosurgical ICU Patients With Artificial Airways

Ventilator-Associated Pneumonia (VAP)Microbiome DysbiosisIntensive Care Unit (ICU) Patients
Jian-Xin Zhou220 enrolled3 locationsNCT07129174
Recruiting

Health-care Quality in Semi-intensive Care Units

EvaluationSemi-intensive Care UnitQuality
Mario Negri Institute for Pharmacological Research39,000 enrolled18 locationsNCT04676347
Recruiting
Not Applicable

Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient

Continuous renal replacement therapyAcute Kidney InjuryIntensive Care Unit
Centre Hospitalier Universitaire de Nīmes80 enrolled1 locationNCT06369064
Recruiting
Phase 3

Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.

AnalgesiaIntensive Care UnitLidocaine
Centre Hospitalier Universitaire, Amiens70 enrolled1 locationNCT03984656
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390
Recruiting
Not Applicable

Comfort Intervention in PICU Children

Anxiety in childrenSleepFear+2 more
Ankara Yildirim Beyazıt University86 enrolled1 locationNCT07441668
Recruiting
Not Applicable

Virtual Reality for Recovery After Intensive Care (PICS)

Cognitive ImpairmentCritical IllnessCritical Illness Recovery+4 more
University of Minho51 enrolled1 locationNCT07585500
Recruiting

CALLY Index, Frailty and SOFA-2 for Mortality Prediction in Geriatric ICU Patients

FrailtyCritical IllnessIntensive Care Unit ICU
Istanbul University - Cerrahpasa100 enrolled1 locationNCT07579728
Recruiting
Not Applicable

Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients

Intradialytic HypotensionHemodialysis PatientsIntensive Care Unit ICU
Chulalongkorn University46 enrolled1 locationNCT07179705
Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

Premature BirthInfant, Extremely PrematureObstetric Labor, Premature+2 more
The University of Texas Health Science Center, Houston5,000 enrolled51 locationsNCT05685745
Recruiting
Not Applicable

Therapeutic Cuddling in Critically Ill Children

PainDelirium in the Intensive Care Unit
University of Calgary112 enrolled1 locationNCT07562048