RecruitingNot ApplicableNCT04355572
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
Sponsor
Yale University
Enrollment
60 participants
Start Date
May 1, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement. Participants and investigators will be blinded to treatment modality until the end of the trial period
Eligibility
Sex: FEMALEMin Age: 13 YearsMax Age: 21 Years
Inclusion Criteria1
- \- Postmenarchal adolescent females aged 13-21 who meet modified Rotterdam criteria for PCOS, with a serum vitamin D level between 6-29 ng/mL.
Exclusion Criteria3
- Other causes for hyperandrogenism,
- Chronic renal diseases,
- Acquired or inherited calcium and vitamin D metabolic disorders.
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Interventions
DRUGVitamin D 4000IU daily
Randomized to receive vitamin D 4000IU daily
DRUGPlacebo
Randomized to placebo daily
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04355572
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