The Olmsted NAFLD Epidemiology Study (TONES)
Mayo Clinic
800 participants
Oct 10, 2020
INTERVENTIONAL
Conditions
Summary
Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.
Eligibility
Inclusion Criteria3
- Olmsted County residents at the time of search
- Age 18 or older
- No personal history of NAFLD diagnosis (administrative codes)
Exclusion Criteria3
- Alcohol in excess (more than 20 gm per week in women and 30 gm per week in men)
- Currently pregnant
- Have contraindications to MRI (MRI incompatible implanted devices, severe claustrophobia)
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Interventions
Combines MRI imaging with sound waves to create a visual map (elastogram) showing the stiffness of body tissues.
Clinical blood tests with a focus on liver function parameters and diabetes
If indicated per MRE results a biopsy will be taken of the liver.
If indicated per MRE results a fibroscan will be performed of the liver.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04365855