Non-Alcoholic Fatty Liver Disease Clinical Trials

58 recruiting

Non-Alcoholic Fatty Liver Disease Trials at a Glance

61 actively recruiting trials for non-alcoholic fatty liver disease are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Boston, New York, and Hong Kong. Lead sponsors running non-alcoholic fatty liver disease studies include The University of Hong Kong, Cairo University, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse non-alcoholic fatty liver disease trials by phase

Treatments under study

About Non-Alcoholic Fatty Liver Disease Clinical Trials

Looking for clinical trials for Non-Alcoholic Fatty Liver Disease? There are currently 58 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Non-Alcoholic Fatty Liver Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Non-Alcoholic Fatty Liver Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 61 trials

Recruiting

Liver Steatosis in Pediatric CD Patients

Non-Alcoholic Fatty Liver DiseaseCeliac Disease in Children
University of Palermo91 enrolled2 locationsNCT06206616
Recruiting

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

Non-Alcoholic Fatty Liver DiseaseLow Birth Weight
Steno Diabetes Center Copenhagen300 enrolled1 locationNCT05890365
Recruiting

Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

Liver NeoplasmLiver FibrosisHBV Infection+1 more
Nanfang Hospital, Southern Medical University240 enrolled1 locationNCT07265544
Recruiting

CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome

Non-Alcoholic Fatty Liver Disease
Institut National de la Santé Et de la Recherche Médicale, France710 enrolled1 locationNCT05623150
Recruiting
Phase 1

Effect of Insulin Lowering on Lipogenesis

ObesityInsulin ResistanceNon-Alcoholic Fatty Liver Disease+2 more
Columbia University25 enrolled1 locationNCT07403604
Recruiting
Phase 1

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin ResistanceNon-Alcoholic Fatty Liver DiseaseOverweight and Obesity+1 more
Columbia University32 enrolled1 locationNCT06354088
Recruiting

Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome

Non-Alcoholic Fatty Liver DiseaseAutoimmune HepatitisPrimary Sclerosing Cholangitis+2 more
Chungnam National University Hospital3,000 enrolled1 locationNCT06519162
Recruiting

Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease
Brigham and Women's Hospital150 enrolled2 locationsNCT05728697
Recruiting
Not Applicable

Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease

Non-Alcoholic Fatty Liver Disease
Weill Medical College of Cornell University40 enrolled1 locationNCT05332613
Recruiting

Identification of Liver Fibrosis Biomarkers

Non-Alcoholic Fatty Liver DiseaseNon-alcoholic Fatty Liver
Roche Diagnostics GmbH575 enrolled2 locationsNCT06819917
Recruiting

Comorbidities Resolution After MGB Surgery and Change in Body Composition

HypertensionNon-Alcoholic Fatty Liver DiseaseSleep Apnea+5 more
All India Institute of Medical Sciences, Bhubaneswar35 enrolled1 locationNCT06015620
Recruiting

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Liver CancerNon-Alcoholic Fatty Liver DiseaseChronic Liver Disease and Cirrhosis
Institut National de la Santé Et de la Recherche Médicale, France800 enrolled1 locationNCT04690972
Recruiting

Integrated Diagnostics for Early Diagnosis of Liver Disease

Non-Alcoholic Fatty Liver Disease
Manchester University NHS Foundation Trust1,200 enrolled1 locationNCT04666402
Recruiting
Phase 2

Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease

Non-Alcoholic Fatty Liver Disease
Justin Ryder40 enrolled1 locationNCT06355310
Recruiting
Not Applicable

The Olmsted NAFLD Epidemiology Study (TONES)

Non-Alcoholic Fatty Liver Disease
Mayo Clinic800 enrolled1 locationNCT04365855
Recruiting
Phase 4

Quantifying Hepatic Mitochondrial Fluxes in Humans

Non-Alcoholic Fatty Liver DiseaseType 2 DiabetesMitochondrial Metabolism Disorders
The University of Texas Health Science Center at San Antonio60 enrolled2 locationsNCT05305287
Recruiting
Not Applicable

Intermittent Fasting for NAFLD in Adults

Non-Alcoholic Fatty Liver DiseaseFatty LiverLiver Fat+2 more
Massachusetts General Hospital25 enrolled1 locationNCT04899102
Recruiting
Not Applicable

Impact of Lifestyle Interventions on Cognitive Decline in Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseNeurocognitive Disorders
Khyber Medical University Peshawar45 enrolled2 locationsNCT07294963
Recruiting
Not Applicable

Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis

NAFLD - Non-Alcoholic Fatty Liver DiseaseMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
ContextVision AB110 enrolled1 locationNCT07270601
Recruiting
Not Applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Insulin Sensitivity/ResistanceObesityInsulin Resistance+14 more
Pichamol Jirapinyo, MD, MPH132 enrolled2 locationsNCT06138821