RecruitingNCT04367883

Influenza Vaccination, ACEI and ARB in the Evolution of SARS-CoV2 Infection

Evaluation of Influenza Vaccination and Treatment With ACEI and ARB in the Evolution of SARS-CoV2 Infection


Sponsor

Consorci Sanitari de Terrassa

Enrollment

3,000 participants

Start Date

Mar 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

Some authors have proposed the use of the flu vaccine to reduce the severity of COVID-19 cases, while some have proposed the use of ACE Inhibitors (ACEI) or Angiotensin Receptor blockers (ARB), since this virus shares hemagglutinin as a transmission mechanism and acts on the ACE2 enzyme during infection. Other authors described how none of the elderly patients receiving antihistamines and azythromycin in two nursing homes in Toledo -Spain- during the first wave died or needed hospital admission, even considering that 100% of residents had a positive serological test after that wave. Other authors have described a positive evolution in patients receiving amantadine for their Parkinson's disease. The aim is to evaluate whether the admitted patients who are previously vaccinated or those who were already receiving these treatments showed a better evolution.


Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ACEI, a drug called ARB, and others for people with ace inhibitors, arb, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAntihistamine

No intervention is performed. We propose an observational study.

DRUGAmantadine

No intervention is performed. We propose an observational study

DRUGACEI

No intervention is performed. We propose an observational study.

DRUGARB

No intervention is performed. We propose an observational study.

OTHERInfluenza vaccine and COVID

No intervention is performed. We propose an observational study.


Locations(1)

Hospital de Terrassa

Terrassa, Barcelona, Spain

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NCT04367883


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