RecruitingNCT04443179

Brain Imaging in Babies Study

Brain Imaging and Infant Development


Sponsor

King's College London

Enrollment

790 participants

Start Date

Apr 5, 2013

Study Type

OBSERVATIONAL

Conditions

Summary

The aims of the BIBS Study The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age. Working with children from a variety of backgrounds and communities, the investigators use a combination of state-of-the-art diagnostic tools such as MRI scans alongside traditional behavioural assessments to capture the earliest information on infant brain development. The focus of the BIBS study MRI scanning is a safe way of producing detailed images using strong magnetic fields and radio waves. It does not use X-ray. Along with learning more about brain development in general, the investigators also try to identify features that may in future help predict whether a child will or will not develop traits of conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). Long-term, this may help target useful interventions early on, helping children who are most in need. Since COVID-19 arrived in the United Kingdom (U.K.) in 2020, the investigators have been given ethical approval to include testing for this infection in the mothers and children participating in the study. This may provide an opportunity to better understand how mother and baby respond to infections. The investigators particularly welcome mothers who have had a positive COVID-19 test during their pregnancy to join the study.


Eligibility

Min Age: 16 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study, called the Brain Imaging in Babies Study, is looking at how early life experiences — including a mother's COVID-19 infection during pregnancy — may affect a baby's brain development. Researchers are particularly interested in babies who have a family history of Autism Spectrum Disorder (ASD) or other neurodevelopmental conditions, as these children may be at higher risk. The study is based in England and involves both pregnant mothers and their infants. By tracking brain development over time, scientists hope to better understand what factors influence a child's neurological health in the earliest stages of life. You may be eligible if: - You are a pregnant mother (with or without a COVID-19 diagnosis) - You have an infant with or without a family history of ASD or neurodevelopmental conditions - You are based in England, UK - You are between 16 and 75 years of age You may NOT be eligible if: - You do not meet additional screening criteria determined by the study team Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

King's College London

London, United Kingdom

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NCT04443179


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