RecruitingNCT04448951
Immune Homeostasis in Sepsis and Septic Shock
Immune Homeostasis in Patients With Sepsis and Septic Shock: a Single Center Observational Study
Sponsor
Charles University, Czech Republic
Enrollment
200 participants
Start Date
Sep 1, 2020
Study Type
OBSERVATIONAL
Conditions
Summary
Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- sepsis/septic shock (SEPSIS-3)
- age ≥18
- informed consent
- inclusion within first 24hrs after development/diagnosis of septic shock
Exclusion Criteria3
- disagreement of the patient or legal representative with the entry into the study
- patients with primary or secondary immunodeficiency
- presence of active haematological malignancy or an active non-haematological malignancy
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Interventions
OTHERtranscriptomics
transcriptomics
OTHERflow-cytometry
peripheral blood myeloid cells and lymphocytes flow-cytometry
OTHERcytokines
peripheral blood cytokine analysis
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04448951
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