RecruitingNCT04449068

Observational Database on Deep Brain Stimulation in Tourette Syndrome

Pre et Post-operative Evaluation of Patients With Tourette Syndrome Treated With High Frequency Bilateral Stimulation of the Anterior Part of the Internal Pallid Globus


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

20 participants

Start Date

Jan 12, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Within an ongoing deep brain stimulation (DBS) program for Tourette syndrome (TS) at the Department of Neurology, Pitié-Salpêtrière Hospital, Paris/France, the investigator team plans to evaluate patients pre-operatively and then at one year intervals post-operatively until the 5-year mark has been achieved. The investigator team will investigate tic severity, psychiatric co-morbidities, quality of life, and neuropsychological measures.


Eligibility

Min Age: 15 Years

Inclusion Criteria2

  • Tourette syndrome severe and drug-resistant eligible for bilateral deep brain stimulation
  • Person who voluntarily and knowledgeably agreed to participate in the study

Exclusion Criteria1

  • Non affiliation to a French social security system (recipient or assign) excluding AME

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Interventions

OTHERNeurological and neuropsychological Follow-up after deep brain stimulation

Investigation of tic severity, psychiatric co-morbidities, quality of life, and neuropsychologcial measures until the 5-year after deep brain stimulation (DBS)

DEVICEEEG recordings

EEG recordings at 2 visits (V1 and V2)


Locations(1)

CIC Neurosciences, GH Pitié-Salpêtrière

Paris, France

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NCT04449068


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