Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid Hemorrhage
Investigation of the Relationship Between Hippocampal Volume and Memory Functions in in Patients With Aneurysmal Subarachnoid Hemorrhage (aSAH)
BDH-Klinik Hessisch Oldendorf
30 participants
Jun 15, 2020
OBSERVATIONAL
Conditions
Summary
Neuropsychological and functional long-term consequences of subarachnoid hemorrhages (SAH) represent a great challenge, since sometimes considerable cognitive deficits occur without evidence of substantial brain damage. In this study, we want to examine if the frequently observed memory deficits are associated with hippocampal atrophy.
Eligibility
Inclusion Criteria5
- neurological rehabilitation patients in phase B - D
- at minimum eight weeks after disease onset
- aneurysmal subarachnoid hemorrhage (Hunt \& Hess grade I or II)
- written consent from the patient's legal representative
- exclusion of pregnancy
Exclusion Criteria7
- insufficient cardiorespiratory stability
- previous brain damage
- mental disorders (dementia, depression)
- colonization with multi-resistant pathogens
- MRI contraindications
- claustrophobia
- weight > 120 kg
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Interventions
Complex neuropsychological assessment testing attentional and memory functions. Additionally, a structural MRI is measured.
Locations(1)
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NCT04449666