RecruitingNot ApplicableNCT04469387

Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion

Preventive Effect of Limited Decompression on Adjacent Segment With Pre-existing Spinal Canal Stenosis Following Posterior Lumbar Interbody Fusion: a Prospective Interventional Study


Sponsor

Peking University Third Hospital

Enrollment

200 participants

Start Date

Sep 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for degenerative disease are prospectively enrolled and followed. Patients enrolled in this study have asymptomatic pre-existing spinal canal stenosis at adjacent segment. This study will focus on the effects of preventative limited decompression at adjacent segment.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • A clear diagnosis of lumbar spinal stenosis, and surgical level of L4-S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);
  • Patients have asymptomatic pre-existing spinal canal stenosis (cerebrospinal fluid occlusion grade=1) at adjacent segment.
  • Failed at least eight weeks conservative treatment;

Exclusion Criteria4

  • Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4;
  • Preoperative sagittal and coronal imbalance of the spine;
  • Lumbar infection and/or tumor diseases;
  • A previous history of lumbar fusion surgery.

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Interventions

PROCEDURELimited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis

In terms of limited decompression at the adjacent segment, partial laminotomy, flavectomy, and bilateral medial facetectomies up to the pedicle will be performed. Complete laminectomy and destroy of posterior ligament complex will be avoided.

PROCEDUREResponsible segments fused

In terms of responsible segments fused, L4-5 and L5-S1 were fused using posterior lumbar interbody fusion (PLIF).


Locations(1)

Peking University Third Hospital

Beijing, Beijing Municipality, China

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NCT04469387


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