Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock
Intérêt du Traitement de la fièvre Par Refroidissement Externe Pour la Survie Des Patients ventilés en Choc Septique
Centre Hospitalier Intercommunal Creteil
820 participants
Oct 1, 2022
INTERVENTIONAL
Conditions
Summary
The best strategy for managing fever in patients with septic shock remains unknown. In a pilot study, the investigators showed that fever control at normothermia allowed a better control of shock and evolution of organ failures. In this second trial the investigators will conduct a multicentre, open-label, randomized controlled, superiority trial in which two strategies will be compared: 1. Respect of fever 2. Fever control at normothermia using external cooling The primary end point will be d-60 mortality.
Eligibility
Plain Language Summary
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Interventions
External Cooling
Locations(33)
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NCT04494074