Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Impact of Decreased Venous Return on Supine Blood Pressure
Vanderbilt University Medical Center
44 participants
Aug 21, 2020
INTERVENTIONAL
Conditions
Summary
Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.
Eligibility
Plain Language Summary
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Interventions
Tilt of the whole bed so that the head is elevated by 9 and/or 12 inches in an acute trial or overnight.
Elevation of the trunk through raising just the head of the bed until the head is elevated by 9 and/or 12 inches in an acute trial or overnight.
Tilt of the whole bed so that the head is elevated by 8 inches overnight.
Elevation of the trunk through raising the head 8 inches on a wedge pillow overnight.
Locations(1)
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NCT04502225