Autonomic Failure Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about Autonomic Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Phase 1

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+2 more
Daniel Claassen40 enrolled1 locationNCT04246437
Recruiting
Not Applicable

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

HypertensionMultiple System AtrophyAutonomic Failure+1 more
Vanderbilt University Medical Center20 enrolled1 locationNCT03042988
Recruiting
Early Phase 1

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center31 enrolled1 locationNCT04620382
Recruiting
Not Applicable

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Autonomic FailureSupine Hypertension
Vanderbilt University Medical Center12 enrolled1 locationNCT03312556
Recruiting
Not Applicable

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

Autonomic FailureSupine Hypertension
Vanderbilt University Medical Center44 enrolled1 locationNCT04502225
Recruiting
Not Applicable

CPAP for the Treatment of Supine Hypertension

Multiple System AtrophyParkinson DiseaseAutonomic Failure+3 more
Vanderbilt University Medical Center59 enrolled1 locationNCT05489575
Recruiting
Phase 1

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center34 enrolled1 locationNCT02897063
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915