Child-Parent Familial Hypercholesterolemia Screening
Child-Parent Screening of Familial Hypercholesterolemia in Children
Children's Hospital of Fudan University
15,000 participants
Apr 1, 2025
OBSERVATIONAL
Conditions
Summary
Child-parent screening for familial hypercholesterolemia has been proposed to identify children and their parent who are carrier of mutations and with high risk for inherited premature coronary artery disease. The investigators assessed the efficacy and feasibility of such screening in primary care practice. key scientific questions: 1. The 95th and 99th percentile of finger blood TC in children of 2 years old. 2. Mutations that contribute to high TC status ( serum TC \>99th percentiles) compared with international FH48 panel for FH genetic screening.
Eligibility
Inclusion Criteria2
- Receive routine child care
- aged 1 - 3 years old ( date of investigate minus date of birth)
Exclusion Criteria1
- It is up to the researcher to decide whether it is suitable to participate in this research
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Interventions
it is a observational study, do not have interventions.
Locations(6)
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NCT04529967