2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)
Vanderbilt University Medical Center
72 participants
Feb 14, 2024
INTERVENTIONAL
Conditions
Summary
The Investigators will test the hypothesis that 2-HOBA will reduce modification of HDL and LDL and improve HDL function in humans with heterozygous FH. The Investigators plan to first study subjects with Familial Hypercholesterolemia (FH), treating them with 750 mg of 2-HOBA or placebo every 8 hours for 6 weeks.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
2-Hydroxybenzylamine (2-HOBA) 250 mg three tabs TID (po) for 6 weeks.
Placebo 250 mg three tabs TID (po) for 6 weeks.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04941599