Supportive-Expressive and Emotion-Focused Treatment for Depression

This study compares two types of talk therapy — supportive-expressive therapy and emotion-focused therapy — for adults with major depression. Researchers want to find out which approach works better and for whom, using brain scans and clinical assessments. **You may be eligible if...** - You are 18–65 years old - You meet the criteria for major depressive disorder and have a moderate-to-severe depression score on a standard scale - You are fluent in Hebrew - If you are on antidepressant medications, your dose has been stable for at least 3 months and you are willing to keep it stable throughout the study - You are not currently in any other psychotherapy **You may NOT be eligible if...** - You are at current risk of suicide or self-harm - You have a current substance use disorder - You have a history of schizophrenia, psychosis, bipolar disorder, or severe eating disorder - You have a history of organic brain disease - You are currently receiving psychotherapy Talk to your doctor to see if this trial is right for you.