Obesity and Pediatric Multiple Sclerosis
Obesity as a Driver of Inflammation and Brain Volume Loss in Pediatric Multiple Sclerosis.
University of Virginia
116 participants
Jun 3, 2021
OBSERVATIONAL
Conditions
Summary
Obesity is one possible contributor to severity of multiple sclerosis and progression of the disease. We already know that obesity is a risk determinant for acquiring MS, yet the impact of obesity on pediatric MS disease expression and course is unknown. This study will evaluate the relationship between obesity, obesity-derived inflammatory mediators, and imaging metrics of MS severity in children. Understanding how childhood obesity contributes to MS severity/progression may yield fundamental insights into disease pathobiology - which may thereby lead to effective strategies for halting its progression in its earliest stages.
Eligibility
Plain Language Summary
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Locations(2)
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NCT04593082