RecruitingPhase 2NCT04597372

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study


Sponsor

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Enrollment

154 participants

Start Date

Nov 3, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of the study is to determine the effectiveness of postoperative Tamsulosin in reducing the duration of acute postoperative urinary retention (POUR) following pelvic reconstructive surgery through a double blind, randomized placebo-controlled trial.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial tests whether tamsulosin — a medication normally used in men with prostate issues to relax bladder outlet muscles — can help women who cannot urinate after pelvic reconstructive surgery. Post-operative urinary retention (inability to pass urine) affects many women after pelvic floor procedures and often requires them to go home with a catheter. Tamsulosin works by relaxing the muscles in the bladder outlet, and this study tests whether it helps women regain normal urination faster after surgery. You may be eligible if: - You are 18 years old or older - You have had pelvic reconstructive surgery and cannot urinate adequately before hospital discharge (failed retrograde void trial) - You can swallow pills and understand English You may NOT be eligible if: - You have an allergy to tamsulosin or sulfa drugs - You had difficulty urinating before surgery (post-void residual over 150 mL) - You already take an alpha-blocker medication for high blood pressure - You have severe dementia, end-stage kidney or liver disease, or recent major cardiovascular event (within 6 months) Talk to your gynecologist or urogynecologist if you experienced urinary retention after pelvic floor surgery and want to know whether a short course of medication might help you avoid prolonged catheter use.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGTamsulosin

Study drug will contain 0.4 mg of Tamsulosin. Subjects will be provided with 10 capsules to be taken daily.

DRUGPlacebo

Placebo will be prepared by the IDS pharmacist (or contracted pharmacy) and encapsulated in identical appearing wraps. Subjects will be provided with 10 capsules to be taken daily.


Locations(1)

West Penn Hospital

Pittsburgh, Pennsylvania, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04597372


Related Trials