RecruitingNCT04608357

Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients

Integrated Patient Avatars for Guiding Systemic Therapy Treatments: "Intuition-Free" Decisions in Metastatic Breast Cancer Patients

Sponsor

Sunnybrook Health Sciences Centre

Enrollment

25 participants

Start Date

Jul 21, 2021

Study Type

OBSERVATIONAL

Conditions

Breast Cancer Metastatic Breast Cancer Breast Neoplasms Cancer, Breast

Summary

The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building personalized computer models ("patient avatars") using cancer tissue samples to help predict which treatments will work best for people with metastatic breast cancer. The goal is to guide treatment decisions more precisely. **You may be eligible if...** - You are 18 or older - You have metastatic breast cancer (any type/subtype) - Your cancer has spread to lymph nodes or internal organs - You have measurable disease that can be tracked on scans - You are willing to have a biopsy of a metastatic site before starting your next treatment **You may NOT be eligible if...** - A biopsy of a metastatic site cannot be safely done (e.g., the tumor is too close to blood vessels or other vital structures) - You are unable to give informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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