Immunonutrition and Tolerance to Chemoradiotherapy in Patients With Head-neck Cancer
Efficacy of Immunonutrition in Improving Tolerance to Chemoradiotherapy in Patients With Head-neck Cancer
Fondazione IRCCS Policlinico San Matteo di Pavia
86 participants
Mar 17, 2021
INTERVENTIONAL
Conditions
Summary
The aim of the present project is to evaluate in a randomised, controlled, open-label, two parallel treatment groups pilot study, the efficacy of oral nutritional supplementation with a high-protein-high calorie mixture containing immunonutrients compared to a standard high-calorie-high-protein nutritional blend, in addition to nutritional counseling, in improving tolerance to chemoradiotherapy (CT-RT) in patients with tumours of the head and neck
Eligibility
Inclusion Criteria3
- diagnosis of head-neck cancer
- indication to curative or adjuvant chemoradiotherapy
- availability to planned measurements and to written informed consent.
Exclusion Criteria3
- age \<18 years
- indication to or ongoing artificial nutrition
- refusal
Interventions
In addition to nutritional counseling, patients will receive two servings of an oral high-calorie-high-protein nutritional liquid supplement enriched in immunonutrients (Impact®). The intervention will start 10-15 days before anticancer treatment initiation and will continue until treatment termination or dropout.
In addition to nutritional counseling, patients will receive two servings of an oral high-calorie-high-protein nutritional liquid supplement. The intervention will start 10-15 days before anticancer treatment initiation and will continue until treatment termination or dropout.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04611113