Sleep Trial to Prevent Alzheimer's Disease

This study is testing whether treating sleep disorders — particularly sleep apnea — in older adults can reduce the risk of developing Alzheimer's disease. It focuses on people who currently show no signs of dementia, with the goal of preventing cognitive decline before it starts. **You may be eligible if...** - You are 65 years old or older - You currently show no signs of dementia (CDR score of 0) - You are willing and able to participate in study procedures, including a sleep test **You may NOT be eligible if...** - You have restless legs syndrome, narcolepsy, or other sleep disorders - You have untreated moderate-to-severe sleep apnea - You use a CPAP/sleep apnea device but use it less than 4 hours a night most nights - Your blood Alzheimer's biomarker test (p-tau 217) is below a certain threshold - You have had a stroke or have chronic kidney disease - You have liver problems or HIV - You have a history of substance or alcohol abuse in the past 6 months Talk to your doctor to see if this trial is right for you.