Sleep Clinical Trials

172 recruiting

Sleep Trials at a Glance

734 actively recruiting trials for sleep are listed on ClinicalTrialsFinder across 6 cities in 58 countries. The largest study group is Not Applicable with 404 trials, with the heaviest enrollment activity in Boston, Philadelphia, and Chicago. Lead sponsors running sleep studies include Chinese University of Hong Kong, VA Office of Research and Development, and University of Pittsburgh.

Treatments under study

About Sleep Clinical Trials

Looking for clinical trials for Sleep? There are currently 172 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 734 trials

Recruiting

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)120 enrolled1 locationNCT05052216
Recruiting
Not Applicable

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

SleepMild Traumatic Brain InjurySleep Architecture+1 more
University of Missouri-Columbia15 enrolled1 locationNCT07385105
Recruiting
Not Applicable

Impact of a Mandibular Oral Repositioning Device on Sleep Quality, Heart Rate Variability, & SpO2

Sleep
University of Calgary24 enrolled1 locationNCT07359638
Recruiting
Not Applicable

Pain Assessment in Patients With Idiopathic Rapid Eye Movement (REM) Sleep Behaviour Disorder

REM Sleep Behavior Disorder (iRBD)Narcolepsy Type 1
University Hospital, Toulouse24 enrolled1 locationNCT07365566
Recruiting
Not Applicable

GUTLINK4KIDS Intervention

SleepCognitionEmotion Regulation+1 more
University of Reading106 enrolled1 locationNCT07401212
Recruiting
Not Applicable

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult
Cryosa, Inc.25 enrolled9 locationsNCT06008626
Recruiting
Phase 1Phase 2

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting

Sleep Quality in Assisted-Living Residents

Sleep DisturbanceAging
University of Calgary150 enrolled1 locationNCT04400617
Recruiting

Sleep Quality and Cognitive Functions in Adults: A Cross-Sectional Study

Sleep QualityCognitive Functions
Uskudar University75 enrolled1 locationNCT07387783
Recruiting
Not Applicable

Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

Sleep Deprivation
University of Guelph30 enrolled1 locationNCT06679543
Recruiting
Not Applicable

The Impact of Melatonin Lotion on Sleep and Mental Health

Sleep ProblemsDepressive Disorder and Anxiety Disorders
University of Redlands60 enrolled1 locationNCT06768749
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Obstructive Sleep Apnea
Amgen250 enrolled38 locationsNCT07226765
Recruiting
Not Applicable

Post Market Clinical Follow up of ResMed Mask Systems

Obstructive Sleep Apnea
ResMed500 enrolled1 locationNCT05262439
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

ObesityObstructive Sleep Apnea
Amgen250 enrolled47 locationsNCT07225686
Recruiting
Not Applicable

Effect of Night Guard Use on Masseter Muscle Thickness in Children With Bruxism

BruxismBruxism, Sleep-Related
Nigde Omer Halisdemir University20 enrolled1 locationNCT07548502
Recruiting
Not Applicable

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

Sleep
Danisco174 enrolled3 locationsNCT07243574
Recruiting
Phase 4

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Sleep DisturbanceAtopic Dermatitis
Northwestern University40 enrolled1 locationNCT05042258
Recruiting
Phase 2

Sleep and Stress Study

StressAnxietySleep Disorder (Disorder)
RDC Clinical Pty Ltd240 enrolled1 locationNCT07315516
Recruiting

OSA as a Remote Ischemic Preconditioning in Vascular Surgery

Obstructive Sleep ApneaIschemia Reperfusion InjuryVascular Aneurysm
St. Anne's University Hospital Brno, Czech Republic100 enrolled1 locationNCT04630535