Sleep Clinical Trials

820 recruitingLast updated: June 17, 2026

There are 820 actively recruiting sleep clinical trials across 61 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, Chicago, Illinois, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Sleep Trials at a Glance

820 actively recruiting trials for sleep are listed on ClinicalTrialsFinder across 6 cities in 61 countries. The largest study group is Not Applicable with 453 trials, with the heaviest enrollment activity in Boston, Chicago, and New York. Lead sponsors running sleep studies include VA Office of Research and Development, Chinese University of Hong Kong, and University of Pittsburgh.

Treatments under study

About Sleep Clinical Trials

Looking for clinical trials for Sleep? There are currently 189 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 820 trials

Recruiting
Not Applicable

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation

Sleep-disordered breathing (SDB)Obstructive Sleep ApneaArrhythmia+3 more
Beijing Anzhen Hospital658 enrolled27 locationsNCT07444372
Recruiting
Not Applicable

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Atrial FibrillationObstructive Sleep Apnea
Tulane University60 enrolled3 locationsNCT04814420
Recruiting
Phase 2

Sleep Trial to Prevent Alzheimer's Disease

SleepAlzheimer Disease
Washington University School of Medicine200 enrolled1 locationNCT04629547
Recruiting

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)120 enrolled1 locationNCT05052216
Recruiting
Not Applicable

The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps

Leg Cramps, NocturnalPoor sleep quality
StudySetGo50 enrolled1 locationNCT07651514
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Obstructive Sleep Apnea
Amgen250 enrolled54 locationsNCT07226765
Recruiting
Phase 1

The Role of the LC-NA System in Experimental Sleep Fragmentation

The Role of the LC-NA System in Sleep Regulation
Hans-Peter Landolt42 enrolled1 locationNCT07167316
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

ObesityObstructive Sleep Apnea
Amgen250 enrolled60 locationsNCT07225686
Recruiting
Not Applicable

Multidimensional Sleep Health Intervention for Couples

Blood PressureSleepCardiovascular Health
Columbia University50 enrolled1 locationNCT07603245
Recruiting
Not Applicable

Evaluating the Impact of Home-Based Sleep Apnea Diagnostic on Well-Being, Health Behavior, and AF Load in Patients With Atrial Fibrillation Using a Decentralized Platform

Sleep ApneaAtrial Fibrillation (AF)
Herlev and Gentofte Hospital936 enrolled1 locationNCT06618417
Recruiting

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

SleepNeurodevelopmental DisorderNeurological Disorder+1 more
National Institute of Mental Health (NIMH)1,000 enrolled1 locationNCT01778504
Recruiting
Not Applicable

Neuroplasticity in RBD

REM Sleep Behavior Disorder
University of Minnesota86 enrolled1 locationNCT05471960
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915
Recruiting
Phase 2

Cannabidiol and Older Adult Cannabis Users

PainDepressionSleep+1 more
University of Colorado, Boulder385 enrolled1 locationNCT06290063
Recruiting
Phase 3

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

ObesityOverweightObstructive Sleep apnoea
Novo Nordisk A/S300 enrolled91 locationsNCT07571109
Recruiting
Not Applicable

Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise

Poor quality sleepStroke
University of British Columbia62 enrolled1 locationNCT06847074
Recruiting
Not Applicable

Sleep TMS for Depression

SleepMajor Depression
Stanford University15 enrolled1 locationNCT06824415
Recruiting
Phase 3

Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Assistance Publique - Hôpitaux de Paris386 enrolled1 locationNCT07047092
Recruiting
Not Applicable

Sensory and Behavioral Sleep Training

Sleep Disorder (Disorder)
Atlas University54 enrolled1 locationNCT07638605
Recruiting

Hospital Environmental Exposure

Air qualitySleepNoise exposure+2 more
University of Leicester120 enrolled1 locationNCT06802367