RecruitingNot ApplicableNCT04651530

Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma


Sponsor

Helsinki University Central Hospital

Enrollment

100 participants

Start Date

Dec 8, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess whether endoscopic cyclophotocoagulation added to cataract surgery lowers intraocular pressure more than cataract surgery alone in patients with normal tension glaucoma.


Eligibility

Min Age: 55 YearsMax Age: 100 Years

Inclusion Criteria4

  • Signed Informed Consent
  • Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle
  • Glaucoma stable with current medication assessed by a glaucoma specialist
  • Clinically significant cataract

Exclusion Criteria18

  • Secondary Glaucoma e.g. due to previous injury or uveitis
  • Exfoliation syndrome
  • Pigment dispersion syndrome
  • Previous transscleral or endoscopic cyclophotocoagulation
  • Previous other glaucoma surgery
  • Cataract due to eye injury or congenital cataract
  • Zonular weakness due to Marfan syndrome or other
  • Previous retinal detachment
  • Previous intraocular surgery like vitrectomy and other retinal surgery
  • Wet age-related macular degeneration
  • Diabetic retonopathy
  • Previous corneal transplant or previous refractive surgery
  • Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars
  • The patient does not want to participate in the study
  • The glaucoma progresses on current IOP
  • The patient does not speak Finnish, Swedish or English
  • Dementia
  • Only eye with vision worse than 20/200 or loss of central visual field

Interventions

PROCEDUREPhaco

phacoemulsification of cataract only

PROCEDUREPhaco+ECP

Endoscopic cyclophotocoagulation is done in the same procedure as phacoemulsification of cataract


Locations(1)

Helsinki University Hospital

Helsinki, Finland

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NCT04651530


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