Natural History Study of Usher Syndrome ( Light4Deaf )

This study is tracking the natural history of Usher syndrome — a rare genetic condition that causes both hearing loss and progressive vision loss (retinitis pigmentosa). People with Usher syndrome are born with hearing impairment or deafness, and then gradually lose their vision, often beginning in childhood or early adulthood. There are three main types (I, II, and III) with differing severities. Understanding how the disease progresses over time is essential for developing better treatments and for planning future clinical trials. Participants will undergo regular hearing and vision assessments, and genetic testing will be performed if a molecular diagnosis has not already been made. This is an observational study — no experimental treatment is involved. You may be eligible if: - You have a clinical or molecular diagnosis of Usher syndrome type I, II, or III - You or your legal representative can provide informed consent - You have health insurance coverage You may NOT be eligible if: - You or your legal representative are unable to understand the study or provide informed consent Talk to your doctor to see if this trial is right for you.