RecruitingNot ApplicableNCT04666103

Function Integrity of Neck Anatomy in Thyroid Surgery

Preserving Function Integrity of Neck Anatomy in Thyroid Surgery: A Randomized Clinical Trial


Sponsor

Wuhan University

Enrollment

1,264 participants

Start Date

Dec 11, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment. Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how well surgeons can preserve the healthy structures of the neck — such as nerves, muscles, and the parathyroid glands — during thyroid surgery. Researchers want to improve surgical techniques and outcomes for patients who need their thyroid gland removed. **You may be eligible if you:** - Have been diagnosed with thyroid cancer on one side of the thyroid gland - Have a benign (non-cancerous) nodule on the other side, confirmed by a fine-needle biopsy before surgery - Have a nodule on the opposite side that is 20mm or smaller and is located within the thyroid gland - Have no confirmed cancer in the lymph nodes in your neck **You may NOT be eligible if you:** - Have had previous surgery on your neck - Have had previous radiation therapy to the neck Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREIntraoperative thermal ablation

After the thyroid lobectomy, the contralateral benign thyroid nodule was treated with intraoperative thermal ablation. The "hydrodissection technique'' was used during the ablation process to prevent recurrent laryngeal nerve, esophageal and other important structures from being destroyed by heat energy.


Locations(1)

Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04666103


Related Trials