A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

This study is developing a personalized surveillance and treatment protocol for patients with Familial Adenomatous Polyposis (FAP) — a hereditary condition that causes many polyps throughout the digestive tract — specifically for patients who have already had their colon or rectum surgically removed. Researchers want to improve how these patients are monitored after surgery to catch and manage any remaining polyps or cancer risk. **You may be eligible if you:** - Have been diagnosed with FAP (by genetic testing or clinical criteria) - Have already undergone surgical removal of your colon (and possibly rectum) - Are 18 years of age or older - Have no cancer detected at your baseline endoscopy after surgery **You may NOT be eligible if you:** - Have cancer detected at baseline endoscopy after surgery - Cannot have all polyps removed during clearing endoscopies - Currently require surgery Talk to your doctor to see if this trial is right for you.