Familial Adenomatous Polyposis Clinical Trials

17 recruiting

Familial Adenomatous Polyposis Trials at a Glance

16 actively recruiting trials for familial adenomatous polyposis are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Ann Arbor, Houston, and Cleveland. Lead sponsors running familial adenomatous polyposis studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), National Cancer Institute (NCI), and Fondazione IRCCS Istituto Nazionale dei Tumori, Milano.

Browse familial adenomatous polyposis trials by phase

Treatments under study

About Familial Adenomatous Polyposis Clinical Trials

Looking for clinical trials for Familial Adenomatous Polyposis? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Familial Adenomatous Polyposis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Familial Adenomatous Polyposis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

Familial Adenomatous Polyposis
University of Michigan Rogel Cancer Center32 enrolled2 locationsNCT06641310
Recruiting

Familial Investigations of Childhood Cancer Predisposition

Hereditary Breast and Ovarian CancerHodgkin LymphomaAdrenocortical Carcinoma+30 more
St. Jude Children's Research Hospital1,500 enrolled1 locationNCT03050268
Recruiting
Phase 1Phase 2

Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis
Recursion Pharmaceuticals Inc.67 enrolled17 locationsNCT05552755
Recruiting
Phase 2

An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis

Colorectal CarcinomaFamilial Adenomatous Polyposis
National Cancer Institute (NCI)38 enrolled4 locationsNCT06557733
Recruiting
Phase 1

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

Colorectal CarcinomaFamilial Adenomatous PolyposisColorectal Adenomatous Polyp+1 more
National Cancer Institute (NCI)36 enrolled5 locationsNCT05630794
Recruiting
Phase 3

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1,000 enrolled2 locationsNCT04677998
Recruiting

A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

Familial Adenomatous Polyposis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1,000 enrolled2 locationsNCT04678011
Recruiting

Integrated Cancer Repository for Cancer Research

Breast CancerLiver CancerEsophageal Cancer+47 more
University of Nebraska999,999 enrolled45 locationsNCT02012699
Recruiting

Duodenal Polyposis Classification in FAP

Familial Adenomatous PolyposisFAPDuodenal Neoplasms+6 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano300 enrolled2 locationsNCT07199127
Recruiting
Not Applicable

Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

Familial Adenomatous PolyposisFAP
Abramson Cancer Center at Penn Medicine20 enrolled1 locationNCT06578637
Recruiting
Not Applicable

Ten Versus Fifteen Centimeter Pouch in IPAA Surgery

Familial Adenomatous PolyposisUlcerative Colitis
Odense University Hospital120 enrolled2 locationsNCT06538402
Recruiting

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis

Familial Adenomatous Polyposis
Western Sydney Local Health District100 enrolled1 locationNCT03471403
Recruiting

Microbial and Environmental Factors Associated with Polyps Development in Familial Adenomatous Polyposis (MicrobEnvironment in FAP)

Familial Adenomatous Polyposis
Hospices Civils de Lyon50 enrolled2 locationsNCT06614738
Recruiting
Phase 3

Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis
Yonsei University28 enrolled1 locationNCT06545526
Recruiting
Not Applicable

Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis

Familial Adenomatous PolyposisDuodenal AdenomaAdenomatous Polyposis Coli
Universitätsklinikum Hamburg-Eppendorf10 enrolled1 locationNCT06435533