Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

This study is evaluating a bone graft substitute called MagnetOs Easypack Putty for use in spinal fusion surgery in the lower back. Spinal fusion joins two or more vertebrae together to stabilize the spine, and bone grafting material helps the bones grow together. This research compares MagnetOs Easypack Putty as a standalone graft material against a mix of demineralized bone matrix or fibers with the patient's own bone (autograft). You may be eligible if: - You are at least 18 years old - You have spinal instability requiring fusion surgery at one or two levels in the lower thoracic or lumbar spine (T11 to S1) - You have failed at least 3 months of conservative treatment (unless the instability is due to acute trauma) - The instability meets defined radiographic criteria (e.g., listhesis, collapsed disc height, or specific injury scores) You may NOT be eligible if: - You need more than a two-level fusion or are expected to need another surgery within a year - You have had previous fusion or decompression at the same levels - You are pregnant or planning to become pregnant within 12 months - You have significant metabolic bone disease (e.g., osteogenesis imperfecta, stage 4+ kidney disease, Paget's disease) - You have active infection, malignancy, or a history of cancer - You are involved in active spinal litigation Talk to your spine surgeon about whether your specific instability pattern and medical history make you a candidate for this study.